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AlloGen public release: Q_theta scorer + PXDesign guidance + Colab demo
chq1155 +1: Claude Opus 4.7 (1M context) Single commit, no prior history.
Contents:
- Q_theta scorer (graph transformer, SE(3)-invariant + ESM-2 conditioning,
~898K params, v4-S2 target-swap checkpoint via Git LFS).
- PXDesign guidance scripts (Langevin / SMC / TDS / classifier) under
code/scripts/pxdesign_guidance/.
- CaM inference sample (96 binder-CaM graphs + matching ESM-2 features).
- Colab demo at notebooks/AlloGen_CaM_demo.ipynb (one-click for biology users:
load scorer, score 96 designs, view ROC/best-of-K, guidance recipe).
- README with method figure, inference quickstart, full Python scoring API.
MIT license.
Co-Authored-By: Claude Opus 4.7 (1M context) <noreply@anthropic.com>